Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer’s disease
We previously showed that simvastatin (SV) restored memory in a mouse model of Alzheimer disease (AD) concomitantly with normalization in protein levels of memory-related immediate early genes in hippocampal CA1 neurons. Here, we investigated age-related changes in the hippocampal memory pathway, an...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Springer Nature
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |