BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy

BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy

Autophagy-mediated mitochondrial degradation plays pivotal roles in both the acquisition and maintenance of pluripotency, but the molecular mechanisms that link autophagy-mediated mitochondrial homeostasis to pluripotency regulation are unclear. Here, we identified that the mitophagy receptor BNIP3...

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Bibliographic Details
Main Authors: Chen, Q. (Author), Li, Z. (Author), Liu, K. (Author), Liu, L. (Author), Sun, H. (Author), Wang, C. (Author), Wang, L. (Author), Xu, Y. (Author), Zhang, H. (Author), Zhang, L. (Author), Zhao, Q. (Author), Zhao, T. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
animal
Animals
autophagy
Autophagy
BNip3 protein, mouse
genetics
homeostasis
Homeostasis
membrane protein
Membrane Proteins
metabolism
Mice
Mitochondria
mitochondrial protein
Mitochondrial Proteins
mitochondrion
mitophagy
Mitophagy
mouse
physiology
protein bcl 2
Proto-Oncogene Proteins c-bcl-2
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