Architecture of the human NALCN channelosome

NALCN regulates the resting membrane potential by mediating the Na+ leak current in neurons, and it functions as a channelosome in complex with FAM155A, UNC79, and UNC80. Dysfunction of the NALCN channelosome causes a broad range of neurological and developmental diseases called NALCN channelopathie...

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Bibliographic Details
Main Authors: Liu, H. (Author), Wu, J. (Author), Yan, Z. (Author), Zhao, Q. (Author), Zhou, L. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Online Access:View Fulltext in Publisher