Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression

Depression is a common non-motor feature of Parkinson’s disease (PD) which confers significant morbidity and is challenging to treat. The thalamus is a key component in the basal ganglia-thalamocortical network critical to the pathogenesis of PD and depression but the precise thalamic subnuclei invo...

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Bibliographic Details
Main Authors:	Bhome, R. (Author), Cole, J.H (Author), Iglesias, J.E (Author), Thomas, G.E.C (Author), Weil, R.S (Author), Zarkali, A. (Author)
Format:	Article
Language:	English
Published:	Nature Research 2022
Subjects:	aged amygdala anterior cingulate antidepressant activity antidepressant agent anxiety Article attention deficit disorder basal ganglion BOLD signal brain cortex brain depth stimulation brain region clinical assessment Clinical Dementia Rating cognition controlled study corpus callosum depression diffusion tensor imaging diffusion weighted imaging disease duration disease severity dorsolateral prefrontal cortex ecosystem resilience electroencephalography female follow up fractional anisotropy functional magnetic resonance imaging gray matter Hamilton Depression Rating Scale hemisphere hippocampal sclerosis hippocampus Hospital Anxiety and Depression Scale human image analysis image segmentation magnetoencephalography major clinical study male mental disease mesencephalon Mini Mental State Examination Montreal cognitive assessment morbidity nerve cell network neural stem cell neuroimaging nuclear magnetic resonance imaging Parkinson disease pathogenesis phenotype positron emission tomography prefrontal cortex pulvinar quality control REM sleep retinal nerve fiber layer thickness schizophrenia signal noise ratio sleep disorder thalamocortical tract thalamus thalamus nucleus tractography transcranial direct current stimulation traumatic brain injury Unified Parkinson Disease Rating Scale visual field white matter working memory
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Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression

Internet

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