Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide association meta-analysis with South Asian T2D cases (n = 16,677) and controls (n = 33,856), followed by combined analyses with Europeans (neff = 231,420). We identify 21 novel genetic loci for significan...

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Main Authors:	Ahmad, M. (Author), Ahsan, H. (Author), Anand, S.S (Author), Below, J.E (Author), Bharadwaj, D. (Author), Boehnke, M. (Author), Bowden, D.W (Author), Chambers, J.C (Author), Chandak, G.R (Author), Chee, M.L (Author), Cheng, C.-Y (Author), de Silva, H.J (Author), Engert, J.C (Author), Gerstein, H.C (Author), Islam, M.T (Author), Jasmine, F. (Author), Kasturiratne, A. (Author), Kato, N. (Author), Kibriya, M. (Author), Kooner, J.S (Author), Lamri, A. (Author), Lee, J.-J (Author), Loh, M. (Author), Mahajan, A. (Author), Mani, K.R (Author), McCarthy, M.I (Author), Mohlke, K.L (Author), Morris, A.P (Author), Ng, H.K (Author), Ng, M.C.Y (Author), Paré, G. (Author), Petty, L.E (Author), Prasad, G. (Author), Sabanayagam, C. (Author), Saleheen, D. (Author), Schmid, K. (Author), Shahriar, M. (Author), Sim, X. (Author), Spracklen, C.N (Author), Takeuchi, F. (Author), Tong, L. (Author), Vujkovic, M. (Author), Wickremasinghe, A.R (Author), Wong, T.Y (Author), Yajnik, C.S (Author), Yusuf, S. (Author), Zhang, W. (Author)
Format:	Article
Language:	English
Published:	Nature Research 2022
Online Access:	View Fulltext in Publisher

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Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

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