CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) have been identified in bacteria, archaea and mitochondria of plants, but not in eukaryotes. Here, we report the discovery of 12,572 putative CRISPRs randomly distributed across the human chromosomes, which we termed hCRISPRs. By us...

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Bibliographic Details
Main Authors: Brouwer, R.W.W (Author), Chinnaiyan, A.M (Author), Fijneman, R.J.A (Author), Halimi, Y. (Author), Hoogstrate, Y. (Author), Janssen, B. (Author), Jenster, G. (Author), Komor, M.A (Author), Louwen, R. (Author), Martens-Uzunova, E.S (Author), Niknafs, Y.S (Author), Saha, C. (Author), Strepis, N. (Author), Stubbs, A. (Author), Swagemakers, S.M.A (Author), Tanmoy, A.M (Author), van de Geer, W.S (Author), van der Spek, P.J (Author), van IJcken, W.F.J (Author), van Riet, J. (Author), Voogd, S. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
Archaea
archaeon
Bacteria
bacterium
clustered regularly interspaced short palindromic repeat
Clustered Regularly Interspaced Short Palindromic Repeats
genetics
Genome, Human
human
human genome
Humans
male
Male
RNA, Small Untranslated
small untranslated RNA
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