Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

Three betacoronaviruses have crossed the species barrier and established human-to-human transmission causing significant morbidity and mortality in the past 20 years. The most current and widespread of these is SARS-CoV-2. The identification of CoVs with zoonotic potential in animal reservoirs sugge...

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Bibliographic Details
Main Authors: Andrabi, R. (Author), Boonyaratanakornkit, J. (Author), Burton, D.R (Author), Homad, L.J (Author), Hurlburt, N.K (Author), Jackson, A.M (Author), Jennewein, M.F (Author), MacCamy, A.J (Author), McGuire, A.T (Author), Ozorowski, G. (Author), Pancera, M. (Author), Sholukh, A.M (Author), Sinha, I. (Author), Stamatatos, L. (Author), Wan, Y.-H (Author), Ward, A.B (Author), Zhou, P. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
animal
Animals
Antibodies, Monoclonal
Antibodies, Neutralizing
Antibodies, Viral
chemistry
coronavirus spike glycoprotein
COVID-19
epitope
Epitopes
monoclonal antibody
neutralizing antibody
SARS-CoV-2
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
virus antibody
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