CircSEC24A (hsa_circ_0003528) interference suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells via miR-421/MMP3 axis

CircSEC24A (hsa_circ_0003528) interference suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells via miR-421/MMP3 axis

Accumulating evidence indicates that circular RNAs (circRNAs) function as conclusive modulators in diverse tumors, including in hepatocellular carcinoma (HCC). Nonetheless, knowledge of the latent mechanisms involving circRNAs in HCC development is insufficient. circSEC24A (hsa_circ_0003528) was dis...

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Bibliographic Details
Main Authors: Zhang, B. (Author), Zhou, J. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2022
Subjects:
Carcinoma, Hepatocellular
Cell Line, Tumor
cell proliferation
Cell Proliferation
circSEC24A
competing endogenous RNA
epithelial mesenchymal transition
Epithelial-Mesenchymal Transition
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
hepatocellular carcinoma (HCC)
hsa_circ_0003528
human
Humans
liver cell carcinoma
Liver Neoplasms
liver tumor
Matrix Metalloproteinase 3
metabolism
microRNA
MicroRNAs
miR-421
MIRN421 microRNA, human
MMP3
MMP3 protein, human
RNA, Circular
stromelysin
tumor cell line
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