Tumor targetable and pH-sensitive polymer nanoparticles for simultaneously improve the Type 2 Diabetes Mellitus and malignant breast cancer

Tumor targetable and pH-sensitive polymer nanoparticles for simultaneously improve the Type 2 Diabetes Mellitus and malignant breast cancer

In the recent study, we have developed novel tumor targetable and pH-sensitive PLGA nanoparticles co-loaded with camptothecin (CPT) and metformin (Metf) to simultaneously improve the Type 2 Diabetes Mellitus (T2DM) and malignant breast cancer. To improve the drug loading efficiency, the hydrophobic...

Full description

Bibliographic Details
Main Authors: Deng, J. (Author), Li, K. (Author), Tang, S. (Author), Wen, P. (Author), Yang, B. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2022
Subjects:
animal
Animals
Breast Neoplasms
breast tumor
camptothecin
Camptothecin
Cell Line, Tumor
chemistry
Diabetes Mellitus, Experimental
Diabetes Mellitus, Type 2
drug delivery system
Drug Delivery Systems
experimental diabetes mellitus
female
Female
human
Humans
Hydrogen-Ion Concentration
malignant breast cancer
Mice
mouse
nanoparticle
nanoparticles
Nanoparticles
non insulin dependent diabetes mellitus
pH
pH-sensitive
polymer
Polymers
tumor cell line
tumor microenvironment
Tumor Microenvironment
tumor targeting
Type 2 Diabetes Mellitus
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items