Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

Decrypting the B cell ontogeny of HIV-1 broadly neutralizing antibodies (bNAbs) is paramount for vaccine design. Here, we characterized IgA and IgG bNAbs of three distinct B cell lineages in a viremic controller, two of which comprised only IgG+ or IgA+ blood memory B cells; the third combined both...

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Main Authors: Bontems, F. (Author), Bouvin-Pley, M. (Author), Braibant, M. (Author), Di Santo, J.P (Author), Dimitrov, J.D (Author), Fernández, I. (Author), Fiquet, O. (Author), Girelli-Zubani, G. (Author), Guivel-Benhassine, F. (Author), Hieu, T. (Author), Hrebík, D. (Author), Lorin, V. (Author), Masse-Ranson, G. (Author), Molinos-Albert, L.M (Author), Mouquet, H. (Author), Péhau-Arnaudet, G. (Author), Planchais, C. (Author), Plevka, P. (Author), Rey, F.A (Author), Sanders, R.W (Author), Scheid, J.F (Author), Schwartz, O. (Author), Seaman, M.S (Author), Walker, B.D (Author)
Format: Article
Language:English
Published: Rockefeller University Press 2022
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