A model for how Gβγ couples Gα to GPCR
Representing ∼5% of the human genome, G-protein-coupled receptors (GPCRs) are a primary target for drug discovery; however, the molecular details of how they couple to heterotrimeric G protein subunits are incompletely understood. Here, I propose a hypothetical initial docking model for the encounte...
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| Format: | Article |
| Language: | English |
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NLM (Medline)
2022
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| Online Access: | View Fulltext in Publisher |