Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium among Older Adults Undergoing Major Elective Surgery

Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium among Older Adults Undergoing Major Elective Surgery

Background: Delirium (an acute change in cognition) is a common, morbid, and costly syndrome seen primarily in aging adults. Despite increasing knowledge of its epidemiology, delirium remains a clinical diagnosis with no established biomarkers to guide diagnosis or management. Advances in proteomics...

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Bibliographic Details
Main Authors: Chan, N.Y (Author), Dillon, S.T (Author), Elias, J.A (Author), Fong, T.G (Author), Inouye, S.K (Author), Joseph, M. (Author), Lee, C.G (Author), Libermann, T.A (Author), Marcantonio, E.R (Author), Ngo, L.H (Author), Otu, H.H (Author), Tripp, B. (Author), Vasunilashorn, S.M (Author), Xie, Z. (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Subjects:
Inflammation
Postoperative
Proteomics
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