C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation

C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation

We have previously shown that C/D box small nucleolar RNAs (snoRNAs) transcribed from the DLK1-DIO3 locus on human chromosome 14 (14q32) are associated with cardiovascular disease. DLK1-DIO3 snoRNAs are 'orphan snoRNAs' that have no known targets. We aimed to identify RNA targets and eluci...

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Bibliographic Details
Main Authors: Boon, R.A (Author), Kremer, V. (Author), Mei, H. (Author), Nossent, A.Y (Author), Papac-Milicevic, N. (Author), Quax, P.H.A (Author), van den Homberg, D.A.L (Author), van der Bent, M.L (Author), van Ingen, E. (Author), Wojta, J. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
animal
Animals
fibroblast
Fibroblasts
genetics
integrin
Integrins
metabolism
methylation
Methylation
Mice
mouse
ribose
Ribose
RNA precursor
RNA Precursors
RNA, Small Nucleolar
small nucleolar RNA
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