The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling

Bromodomain-containing protein 7 (BRD7) has been shown to interact with the regulatory subunit of phosphatidylinositol 3-kinase (PI3K), p85, in the insulin signaling pathway. Here, we show that upregulation of hepatic BRD7 improves glucose homeostasis even in the absence of either p85 isoform, p85α...

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Bibliographic Details
Main Authors: Lee, J.M (Author), Liu, R. (Author), Park, S.W (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Akt
Online Access:View Fulltext in Publisher