The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling
Bromodomain-containing protein 7 (BRD7) has been shown to interact with the regulatory subunit of phosphatidylinositol 3-kinase (PI3K), p85, in the insulin signaling pathway. Here, we show that upregulation of hepatic BRD7 improves glucose homeostasis even in the absence of either p85 isoform, p85α...
Main Authors: | Lee, J.M (Author), Liu, R. (Author), Park, S.W (Author) |
---|---|
Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |
Similar Items
-
The interaction of the p85 subunit of PI3K with rab proteins
by: Chamberlain, Michael Dean
Published: (2007) -
LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells
by: Zifeng Wang, et al.
Published: (2019-08-01) -
The role for the p85 subunit of PI3kinase in the regulation of rab proteins
by: King, Jennifer C
Published: (2009) -
The role for the p85 subunit of PI3kinase in the regulation of rab proteins
Published: (2008) -
Marek’s Disease Virus Activates the PI3K/Akt Pathway Through Interaction of Its Protein Meq With the P85 Subunit of PI3K to Promote Viral Replication
by: Huimin Li, et al.
Published: (2018-10-01)