Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

The 48 human nuclear receptors (NRs) form a superfamily of transcription factors that regulate major physiological and pathological processes. Emerging evidence suggests that NR crosstalk can fundamentally change our understanding of NR biology, but detailed molecular mechanisms of crosstalk are lac...

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Main Authors: Annu, K. (Author), Buchman, C.D (Author), Bwayi, M.N (Author), Chai, S.C (Author), Chen, T. (Author), Chodankar, S. (Author), Garcia-Maldonado, E. (Author), Huber, A.D (Author), Lee, H.-M (Author), Peng, J. (Author), Seetharaman, J. (Author), Wang, J. (Author), Wright, W.C (Author), Wu, J. (Author), Xie, B. (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
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