8-oxodG accumulation within super-enhancers marks fragile CTCF-mediated chromatin loops
8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a major product of the DNA oxidization process, has been proposed to have an epigenetic function in gene regulation and has been associated with genome instability. NGS-based methodologies are contributing to the characterization of the 8-oxodG function...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2022
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| Online Access: | View Fulltext in Publisher |