I-Motif formation and spontaneous deletions in human cells

Concatemers of d(TCCC) that were first detected through their association with deletions at the RACK7 locus, are widespread throughout the human genome. Circular dichroism spectra show that d(GGGA)n sequences form G-quadruplexes when n > 3, while i-motif structures form at d(TCCC)n sequences at n...

Full description

Bibliographic Details
Main Authors: Abdelhamid, M.A.S (Author), Chikhale, R.V (Author), Martella, M. (Author), Pichiorri, F. (Author), Smith, S.S (Author), Waller, Z.A.E (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Online Access:View Fulltext in Publisher