Sustained HIV Viral Suppression with Dolutegravir, Tenofovir, and Emtricitabine as Initial Therapy Despite High-Level Transmitted Multiclass Resistance

Sustained HIV Viral Suppression with Dolutegravir, Tenofovir, and Emtricitabine as Initial Therapy Despite High-Level Transmitted Multiclass Resistance

Multiclass high-level transmitted HIV drug resistance is uncommon, and the selection of the optimal initial antiretroviral drug regimen may be challenging. We report a case of extensive transmitted multiclass resistance successfully treated with dolutegravir, tenofovir, and emtricitabine even though...

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Bibliographic Details
Main Authors: Nagami, E.H (Author), Sax, P.E (Author), Thakarar, K. (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Subjects:
abacavir
adult
antiretroviral therapy
antiviral activity
antiviral resistance
Article
case report
CD4 lymphocyte count
clinical article
darunavir
DNA strand
dolutegravir
drug efficacy
drug resistance
electroencephalography
emtricitabine
gene mutation
genotype
HIV
human
Human immunodeficiency virus infection
integrase
integrase strand transfer inhibitor
interferon
lamivudine
nonhuman
pre-exposure prophylaxis
programmed death 1 receptor
risk factor
sexual health
stavudine
tenofovir
virus load
virus replication
zidovudine
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