Reduced Levels of NAD in Skeletal Muscle and Increased Physiologic Frailty Are Associated with Viral Coinfection in Asymptomatic Middle-Aged Adults

Reduced Levels of NAD in Skeletal Muscle and Increased Physiologic Frailty Are Associated with Viral Coinfection in Asymptomatic Middle-Aged Adults

Background: People living with HIV (PLWH) are disproportionately burdened with multimorbidity and decline in physiologic function compared with their uninfected counterparts, but biological mechanisms that differentially contribute to the decline in muscle function in PLWH compared with uninfected p...

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Bibliographic Details
Main Authors: Ghattas, C. (Author), Lau, J. (Author), Li, Z. (Author), Montano, M. (Author), Pencina, K.M (Author), Schultz, M.B (Author), Sinclair, D.A (Author), Tran, T. (Author)
Format: Article
Language:English
Published: Lippincott Williams and Wilkins 2022
Subjects:
cohort analysis
Cohort Studies
coinfection
Coinfection
complication
female
Female
frailty
Frailty
HIV
HIV Infections
human
Human immunodeficiency virus infection
Humans
Inflammation
male
Male
middle aged
Middle Aged
Muscle
Muscle, Skeletal
NAD
nicotinamide adenine dinucleotide
Physiologic frailty
skeletal muscle
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