Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae

Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae

Streptococcus pneumoniae is a major human pathogen that can cause severe invasive diseases such as pneumonia, septicaemia and meningitis. Young children are at a particularly high risk, with an estimated 3-4 million cases of severe disease and between 300 000 and 500 000 deaths attributable to pneum...

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Main Authors: Bentley, S. (Author), Bonini, D. (Author), Brignoli, T. (Author), Carlile, S. (Author), Croucher, N.J (Author), Dillingham, M.S (Author), Dixon, R. (Author), Duggan, S. (Author), Earle, S.G (Author), Jenkinson, H. (Author), Lees, J.A (Author), Massey, R.C (Author), McLoughlin, R.M (Author), Morse, D.J (Author), Nobbs, A. (Author), Recker, M. (Author), Stevens, E.J (Author), Thibault, D. (Author), van Opijnen, T. (Author), Wilkinson, O.J (Author), Wilson, D.J (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
ICE elements
pneumolysin regulation
Streptococcus pneumoniae
ZomB protein
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