Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

Resistance to piperacillin/tazobactam (TZP) in Escherichia coli has predominantly been associated with mechanisms that confer resistance to third-generation cephalosporins. Recent reports have identified E. coli strains with phenotypic resistance to piperacillin/tazobactam but susceptibility to thir...

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Bibliographic Details
Main Authors: Adams, E.R (Author), Bulgasim, I. (Author), Corless, C. (Author), Cuevas, L.E (Author), Edwards, T. (Author), Fraser, A.J (Author), Heinz, E. (Author), Howard, A. (Author), Hubbard, A.T.M (Author), Mason, J. (Author), Parry, C.M (Author), Roberts, A.P (Author), Roberts, P. (Author), van Aartsen, J. (Author), Williams, C.T (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
AMR
Anti-Bacterial Agents
antiinfective agent
bloodstream infection
cephalosporin derivative
Cephalosporins
Escherichia coli
Escherichia coli infection
Escherichia coli Infections
genetics
human
Humans
Piperacillin, Tazobactam Drug Combination
piperacillin/tazobactam
resistance
sepsis
Sepsis
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