Treatment of metastatic cutaneous squamous cell carcinoma in a solid organ transplant recipient with programmed death-1 checkpoint inhibitor therapy

Treatment of metastatic cutaneous squamous cell carcinoma in a solid organ transplant recipient with programmed death-1 checkpoint inhibitor therapy

Limited data exist on the use of immune checkpoint inhibitors (ICI) for the treatment of metastatic cutaneous squamous cell carcinoma (CSCC) in solid organ transplant recipients (SOTR). We report a case of a SOTR who developed metastatic disease following multiple surgeries, three cycles of adjuvant...

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Bibliographic Details
Main Authors: O'Connell, K.A (Author), Schmults, C.D (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2022
Subjects:
aged
allotransplantation
Article
cancer radiotherapy
cancer recurrence
carboplatin
Carcinoma, Squamous Cell
case report
cemiplimab
cetuximab
clinical article
drug megadose
drug rechallenge
drug withdrawal
graft recipient
human
Humans
immunoglobulin
immunosuppressive treatment
kidney allograft rejection
kidney polycystic disease
kidney transplantation
lung metastasis
male
Male
metastatic cutaneous squamous cell carcinoma
Mohs micrographic surgery
mycophenolate mofetil
organ transplantation
Organ Transplantation
pembrolizumab
perineural invasion
positron emission tomography
prednisone
programmed death 1 receptor
rapamycin
skin carcinoma
skin graft
Skin Neoplasms
skin tumor
solid organ transplant recipient
squamous cell carcinoma
steroid
surgical margin
tacrolimus
thorax pain
Transplant Recipients
Transplantation, Homologous
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