Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease

Aims: Reactive astrocytes in Alzheimer's disease (AD) have traditionally been demonstrated by increased glial fibrillary acidic protein (GFAP) immunoreactivity; however, astrocyte reaction is a complex and heterogeneous phenomenon involving multiple astrocyte functions beyond cytoskeletal remod...

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Bibliographic Details
Main Authors: Das, S. (Author), Hyman, B.T (Author), Merrill, E. (Author), Noori, A. (Author), Serrano-Pozo, A. (Author), Viejo, L. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2022
Online Access:View Fulltext in Publisher