Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease
Aims: Reactive astrocytes in Alzheimer's disease (AD) have traditionally been demonstrated by increased glial fibrillary acidic protein (GFAP) immunoreactivity; however, astrocyte reaction is a complex and heterogeneous phenomenon involving multiple astrocyte functions beyond cytoskeletal remod...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
John Wiley and Sons Inc
2022
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Online Access: | View Fulltext in Publisher |