First trimester plasma microRNAs levels predict Matsuda Index-estimated insulin sensitivity between 24th and 29th week of pregnancy

First trimester plasma microRNAs levels predict Matsuda Index-estimated insulin sensitivity between 24th and 29th week of pregnancy

INTRODUCTION: Gestational diabetes mellitus (GDM) is a consequence of an imbalance between insulin sensitivity (IS) and secretion during pregnancy. MicroRNAs (miRNAs) are small and secreted RNA molecules stable in blood and known to regulate physiological processes including glucose homeostasis. The...

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Bibliographic Details
Main Authors: Bouchard, L. (Author), Clément, A.-A (Author), Desgagné, V. (Author), Guérin, R. (Author), Hivert, M.-F (Author), Jacques, P. (Author), Légaré, C. (Author), Perron, P. (Author), Poirier, C. (Author), Scott, M.S (Author), Thibeault, K. (Author), White, F. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
body mass
Body Mass Index
Diabetes, Gestational
epigenetics
female
Female
first trimester pregnancy
genetics
gestational diabetes mellitus (GDM)
human
Humans
insulin resistance
Insulin Resistance
microRNA
MicroRNAs
next-generation sequencing
pregnancy
Pregnancy
pregnancy diabetes mellitus
Pregnancy Trimester, First
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