Tenecteplase Reperfusion therapy in Acute ischaemic Cerebrovascular Events-II (TRACE II): rationale and design

BACKGROUND AND PURPOSE: Tenecteplase (TNK) is a promising agent for treatment of acute ischaemic stroke (AIS). We hypothesised that recombinant human TNK tissue-type plasminogen activator (rhTNK-tPA) is non-inferior to rt-PA in achieving excellent functional outcome at 90 days, when administered wit...

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Main Authors: Campbell, B.C.V (Author), Fisher, M. (Author), Li, H. (Author), Li, S. (Author), Pan, Y. (Author), Parsons, M. (Author), Schwamm, L.H (Author), TRACE II investigators (Author), Wang, Y. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
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