The atlas of ACE2 expression in fetal and adult human hearts reveals the potential mechanism of heart-injured patients infected with SARS-CoV-2

The atlas of ACE2 expression in fetal and adult human hearts reveals the potential mechanism of heart-injured patients infected with SARS-CoV-2

Numerous studies have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect host cells through binding to angiotensin I converting enzyme 2 (ACE2) expressing in various tissues and organs. In this study, we deeply analyzed the single-cell expression profiles of ACE2 in f...

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Bibliographic Details
Main Authors: Feng, R. (Author), Hao, L. (Author), Hou, X. (Author), Shao, X. (Author), Wu, F. (Author), Yi, W. (Author), Zhang, R. (Author), Zhang, X. (Author), Zhu, R. (Author)
Format: Article
Language:English
Published: American Physiological Society 2022
Subjects:
ACE2
adult
Adult
Angiotensin-Converting Enzyme 2
COVID-19
dipeptidyl carboxypeptidase
embryonic development
female
Female
genetics
heart failure
human
Humans
metabolism
molecular docking
Molecular Docking Simulation
Peptidyl-Dipeptidase A
pregnancy
Pregnancy
RAS system
renin angiotensin aldosterone system
Renin-Angiotensin System
SARS-CoV-2
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