MRI-Based Radiotherapy Planning to Reduce Rectal Dose in Excess of Tolerance

MRI-Based Radiotherapy Planning to Reduce Rectal Dose in Excess of Tolerance

Background and Purpose. Chronic rectal toxicity significantly decreases the quality of life for men who receive radiotherapy for prostate cancer. The most significant predictor of rectal toxicity is rectal dose-volume exceeding tolerance. To minimize the volume of rectum in the high dose field, it i...

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Bibliographic Details
Main Authors: Bhagwat, M. (Author), Chen, M.-H (Author), D'Amico, A.V (Author), Glazer, D.I (Author), Loffredo, M.J (Author), McMahon, E. (Author), Moteabbed, M. (Author), Schmidt, D.R (Author), Tempany, C.M (Author)
Format: Article
Language:English
Published: Hindawi Limited 2022
Subjects:
adult
anatomical variation
androgen deprivation therapy
antineoplastic hormone agonists and antagonists
Article
cancer control
clinical article
comparative study
controlled study
dose volume histogram
equivalent uniform dose
human
image guided radiotherapy
image registration
intensity modulated radiation therapy
local therapy
lymph node metastasis
male
nuclear magnetic resonance imaging
organ size
organs at risk
patient-reported outcome
pelvis radiography
planning target volume
prescription
prospective study
prostate adenocarcinoma
prostate volume
radiation injury
radiation response
radiation tolerance
radiotherapy dosage
rectum
rectum disease
treatment planning
tumor invasion
tumor volume
volumetric modulated arc therapy
x-ray computed tomography
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