EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

Gene expression is regulated by promoters and enhancers marked by histone H3 lysine 27 acetylation (H3K27ac), which is established by the paralogous histone acetyltransferases (HAT) EP300 and CBP. These enzymes display overlapping regulatory roles in untransformed cells, but less characterized roles...

Full description

Bibliographic Details
Main Authors: Abraham, B.J (Author), Bikowitz, M.J (Author), Bulyk, M.L (Author), Conway, A.S (Author), Dharia, N.V (Author), Durbin, A.D (Author), Easton, J. (Author), Li, D. (Author), Look, A.T (Author), Mariani, L. (Author), Maxham, L. (Author), Morita, K. (Author), Mundada, M. (Author), Nance, S. (Author), Park, P.M.C (Author), Patel, A.G (Author), Perez-Atayde, A.R (Author), Qi, J. (Author), Quinn, T.R (Author), Robichaud, A.L (Author), Schönbrunn, E. (Author), Shao, Y. (Author), Shendy, N.A.M (Author), Sigua, L.H (Author), Stegmaier, K. (Author), Wang, T. (Author), Wiest, O. (Author), Wimalasena, V.K (Author), Zimmerman, M.W (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items