Hematologic complications with age in Shwachman-Diamond syndrome

Hematologic complications with age in Shwachman-Diamond syndrome

Shwachman-Diamond syndrome (SDS) is an inherited bone marrow failure syndrome with leukemia predisposition. An understanding of the hematologic complications of SDS with age could guide clinical management, but data are limited for this rare disease. We conducted a cohort study of 153 subjects from...

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Bibliographic Details
Main Authors: Bertuch, A.A (Author), Davies, S.M (Author), Fleming, M.D (Author), Furutani, E. (Author), Galvin, A. (Author), Gansner, J.M (Author), Geddis, A.E (Author), Hanna, R. (Author), Keel, S.B (Author), Larson, J.H (Author), Lau, B.W (Author), Lipton, J.M (Author), Liu, S. (Author), Lorsbach, R. (Author), Loveless, S.K (Author), Malsch, M.M (Author), Mount, L. (Author), Myers, K.C (Author), Nakano, T.A (Author), Queenan, K. (Author), Shimamura, A. (Author), Steltz, S. (Author), Vlachos, A. (Author), Wang, W.C (Author), Weller, E. (Author)
Format: Article
Language:English
Published: American Society of Hematology 2022
Subjects:
absolute neutrophil count
acute myeloid leukemia
adolescent
adult
age
alemtuzumab
aplastic anemia
Article
bone marrow biopsy
bone marrow depression
child
chromosome aberration
cohort analysis
cyclophosphamide
decubitus
deep vein thrombosis
diffuse large B cell lymphoma
disease registry
doxorubicin
drug withdrawal
exocrine pancreatic insufficiency
female
fever
fludarabine
gene
gene mutation
granulocyte colony stimulating factor
hematologic disease
hematopoietic stem cell transplantation
hemoglobin
heterozygote
human
human tissue
infant
intrauterine growth retardation
major clinical study
male
mediastinum mass
melphalan
multiple cycle treatment
myelodysplastic syndrome
neutropenia
overall survival
platelet count
pleura effusion
point mutation
polymerase chain reaction
prednisone
rituximab
SBDS gene
Shwachman syndrome
side effect
thymocyte antibody
treosulfan
vincristine
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