Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women

Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women

Background: Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the performance...

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Bibliographic Details
Main Authors: Hao, Y. (Author), Hou, C. (Author), Li, J. (Author), Song, H. (Author), Xu, B. (Author), Yang, D. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Artificial neural network
Breast cancer
Breast Neoplasms
breast tumor
case control study
Case-Control Studies
Estrogen receptor-negative breast cancer
female
Female
genetic predisposition
Genetic Predisposition to Disease
genetics
genome-wide association study
Genome-Wide Association Study
human
Humans
Polygenic risk score
Polymorphism, Single Nucleotide
risk factor
Risk Factors
single nucleotide polymorphism
Single nucleotide polymorphisms
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