Single-cell analysis of p53 transitional dynamics unravels stimulus- and cell type-dependent signaling output motifs

Background: To understand functional changes of complex biological networks, mathematical modeling of network topologies provides a quantitative measure of the way biological systems adapt to external stimuli. However, systemic network topology-based analysis often generates conflicting evidence dep...

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Bibliographic Details
Main Authors: Liang, X. (Author), Liu, B. (Author), Shi, J. (Author), Xie, J. (Author), Zhang, L. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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Online Access:View Fulltext in Publisher