B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer

Introduction: B7-H4 is overexpressed in colorectal cancer (CRC) and plays an important role in tumor growth and immunosuppression. However, the exact mechanism that regulates B7-H4 expression remains largely unknown. Here, we investigated whether protein kinase C δ (PKCδ) regulates the expression of...

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Bibliographic Details
Main Authors: Chen, W. (Author), Lu, Y. (Author), Shi, T. (Author), Wu, H. (Author), Zhang, L. (Author), Zhang, X. (Author), Zhao, Z. (Author), Zhou, B. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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