Preclinical safety and hepatotoxicity evaluation of biomineralized copper sulfide nanoagents

Preclinical safety and hepatotoxicity evaluation of biomineralized copper sulfide nanoagents

Albumin-biomineralized copper sulfide nanoparticles (Cu2−xS NPs) have attracted much attention as an emerging phototheranostic agent due to their advantages of facile preparation method and high biocompatibility. However, comprehensive preclinical safety evaluation is the only way to meet its furthe...

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Bibliographic Details
Main Authors: Ding, H. (Author), Guo, H. (Author), Jiang, T. (Author), Li, X. (Author), Wang, Y. (Author), Xia, Y.-N (Author), Yang, S. (Author), Yu, H. (Author), Zhang, L.W (Author), Zhang, S. (Author), Zu, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Biocompatibility
Biomineralization
Bovine serum albumins
Clinical translation
Copper compounds
Cu2−xS nanoagent
Cu2−xS nanoagents
Facile preparation
Gene expression
Genes expression
Hepatotoxicity
Infrared devices
Kupffer cells
Light absorption
Mammals
Metabolism
Metabolism pathway
Metal ions
Molecular biology
Pathology
Preparation method
Recovery
Safety evaluation
Safety evaluations
Sulfur compounds
Toxicity
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