Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration
Background: Synapse degeneration is an early event in pathological frontotemporal lobar degeneration (FTLD). Consequently, a surrogate marker of synapse loss could be used to monitor early pathologic changes in patients with underlying FTLD. The aim of this study was to evaluate the relationship of...
Main Authors: | Alcolea, D. (Author), Belbin, O. (Author), Cervantes González, A. (Author), Chen-Plotkin, A. (Author), Dols-Icardo, O. (Author), Fortea, J. (Author), Grossman, M. (Author), Illán-Gala, I. (Author), Irwin, D.J (Author), Lee, E.B (Author), Lleó, A. (Author), McMillan, C.T (Author), Querol-Vilaseca, M. (Author), Santos-Santos, M.A (Author), Sirisi, S. (Author), Trojanowski, J.Q (Author), Wolk, D. (Author) |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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