Cortical microstructure in primary progressive aphasia: a multicenter study

Cortical microstructure in primary progressive aphasia: a multicenter study

Background: Cortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical changes....

Full description

Bibliographic Details
Main Authors: Alcolea, D. (Author), Bargalló, N. (Author), Bejanin, A. (Author), Belbin, O. (Author), Blesa, R. (Author), Borrego-Écija, S. (Author), Dickerson, B.C (Author), Dols-Icardo, O. (Author), Falgàs, N. (Author), Fortea, J. (Author), González-Ortiz, S. (Author), Gorno-Tempini, M.L (Author), Illán-Gala, I. (Author), Lladó, A. (Author), Lleó, A. (Author), Mandelli, M.L (Author), Miller, B.L (Author), Montal, V. (Author), Pegueroles, J. (Author), Rosen, H.J (Author), Sánchez-Saudinós, M.B (Author), Sánchez-Valle, R. (Author), Santos-Santos, M. (Author), Welch, A.E (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
aged
Alzheimer’s disease
Aphasia, Primary Progressive
Article
biological marker
brain cortex
brain region
case control study
Case-Control Studies
Clinical Dementia Rating
clinical protocol
clinical trial
controlled study
cortical mean diffusivity
cortical thickness (brain)
diagnostic imaging
Diffusion
Diffusion Magnetic Resonance Imaging
diffusion weighted imaging
disease association
disease severity
female
Frontotemporal lobar degeneration
gene
genetic variability
GRN gene
human
Humans
Magnetic resonance
Magnetic Resonance Imaging
major clinical study
male
mean diffusivity
multicenter study
neuroanatomy
nuclear magnetic resonance imaging
primary progressive aphasia
Primary progressive aphasia
semantics
sensitivity analysis
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items