Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin

Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin

Background: Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the forebrain (BCAS2 cKO) of mice confers impaired learning and memory along with decreased β-catenin expression. Because β-catenin reportedly regulates adult...

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Main Authors: Chang, C.-H (Author), Chen, H.-H (Author), Chen, S.-L (Author), Chen, Y.-W (Author), Huang, C.-W (Author), Huang, H.-S (Author), Lin, S.-H (Author), Lin, Y.-R (Author), Lu, H.-Y (Author), Tsao, Y.-P (Author), Wang, P.-Y (Author), Wei, P.-H (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
AAV-DJ8
Adult neurogenesis
BCAS2
DCX+ immature neurons
Sox2+
β-catenin
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