Menstrual blood-derived mesenchymal stromal cells efficiently ameliorate experimental autoimmune encephalomyelitis by inhibiting T cell activation in mice

Menstrual blood-derived mesenchymal stromal cells efficiently ameliorate experimental autoimmune encephalomyelitis by inhibiting T cell activation in mice

Background: Immunosuppressive properties grant mesenchymal stromal cells (MSCs) promising potential for treating autoimmune diseases. As autologous MSCs suffer from limited availability, the readily available allogeneic MSCs isolated from menstrual blood (MB-MSCs) donated by young, healthy individua...

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Bibliographic Details
Main Authors: Brunner, T.M (Author), Gao, H. (Author), Hu, X. (Author), Li, M. (Author), Li, Y. (Author), Lin, J. (Author), Liu, Q. (Author), Liu, Y. (Author), Löhning, M. (Author), Qiao, L. (Author), Shen, P. (Author), Wu, P. (Author), Yan, Y. (Author), Yang, F. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
animal
Animals
Antigen-presenting cells
C57BL mouse
cell differentiation
Cell Differentiation
Encephalomyelitis, Autoimmune, Experimental
experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis
lymphocyte activation
Lymphocyte Activation
Menstrual blood-derived mesenchymal stromal cells
mesenchymal stem cell
mesenchymal stem cell transplantation
Mesenchymal Stem Cell Transplantation
Mesenchymal Stem Cells
Mice
Mice, Inbred C57BL
mouse
Multiple sclerosis
Ready-to-use allo-MSCs
T cell activation suppression
Th17 cell
Th17 Cells
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