Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress

Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress

Background: Radiotherapy is commonly used to treat childhood cancers and can have adverse effects on muscle function, but the underlying mechanisms have yet to be fully elucidated. We hypothesized that endurance exercise following radiation treatment would improve skeletal muscle function. Methods:...

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Bibliographic Details
Main Authors: Bachman, J.F (Author), Chakkalakal, J.V (Author), Dirksen, R.T (Author), Hernady, E. (Author), Johnston, C.J (Author), Kallenbach, J.G (Author), O’Connor, T.N (Author), Orciuoli, H.M (Author), Paris, N.D (Author), Williams, J.P (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Calcium handling
Exercise
Mitochondria
Muscle
Oxidative/nitrosative stress
Physiology
Radiation
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