Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Background: Aberrant Wnt signalling, regulating cell development and stemness, influences the development of many cancer types. The Aryl hydrocarbon receptor (AhR) mediates tumorigenesis of environmental pollutants. Complex interaction patterns of genes assigned to AhR/Wnt-signalling were recently a...

Full description

Bibliographic Details
Main Authors: Albanes, D. (Author), Aldrich, M.C (Author), Amos, C.I (Author), Andrew, A.S (Author), Arnold, S.M (Author), Bickeböller, H. (Author), Bojesen, S.E (Author), Brennan, P. (Author), Caporaso, N.E (Author), Chen, C. (Author), Christiani, D.C (Author), Cox, A. (Author), Davies, M.P.A (Author), Doherty, J.A (Author), Duell, E.J (Author), Fernández-Tardón, G. (Author), Field, J.K (Author), Goodman, G.E (Author), Haugen, A. (Author), Hung, R.J (Author), Johansson, M. (Author), Kiemeney, L.A (Author), Lam, S. (Author), Landi, M.T (Author), Lazarus, P. (Author), Le Marchand, L. (Author), Liloglou, T. (Author), Liu, G. (Author), Muley, T.R (Author), Muttray, N. (Author), Rennert, G. (Author), Risch, A. (Author), Rosenberger, A. (Author), Schabath, M.B (Author), Shete, S.S (Author), Tardon, A. (Author), Taylor, F. (Author), The INTEGRAL-ILCCO Consortium (Author), Wendel, B. (Author), Woll, P.J (Author), Zienolddiny, S. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
adult
AhR gene
aromatic hydrocarbon receptor
Article
Association
Axin2 gene
cancer risk
cancer susceptibility
controlled study
decision tree
Decision trees
DKK2 gene
DKK3 gene
DKK4 gene
European
female
FRZB gene
gene
gene interaction
Gene–gene integration
genetic variability
genome-wide association study
human
human tissue
lung cancer
major clinical study
male
middle aged
never smoker
Never smoker
Polygenic risk score
Prediction
predictive value
secreted frizzled related protein 4
SFRP4 gene
single nucleotide polymorphism
small cell lung cancer
Small cell lung cancer
smoking
Susceptibility
Wnt gene
Wnt protein
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items