Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers

Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers

PURPOSE In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary thyroid cancer samples reported by The Cancer Genome Atlas project suggested that reclassification of thyroid cancer into molecular subtypes, RAS-like and BRAF-like, better reflects clinical behavior than sole r...

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Bibliographic Details
Main Authors: Adzick, N.S (Author), Bauer, A.J (Author), DeHart, J.C (Author), Franco, A.T (Author), Isaza, A. (Author), Jain, N. (Author), Jones, Z. (Author), Kazahaya, K. (Author), Laetsch, T.W (Author), Li, M.M (Author), Mostoufi-Moab, S. (Author), Reichenberger, E. (Author), Ricarte-Filho, J.C (Author), Surrey, L. (Author), Taylor, D. (Author)
Format: Article
Language:English
Published: Lippincott Williams and Wilkins 2022
Subjects:
adult
Adult
B Raf kinase
child
Child
gene fusion
Gene Fusion
genetics
human
Humans
mutation
Mutation
oncogene
Oncogenes
pathology
Proto-Oncogene Proteins B-raf
Thyroid Cancer, Papillary
Thyroid Neoplasms
thyroid tumor
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