Validation-based model selection for 13C metabolic flux analysis with uncertain measurement errors

Accurate measurements of metabolic fluxes in living cells are central to metabolism research and metabolic engineering. The gold standard method is model-based metabolic flux analysis (MFA), where fluxes are estimated indirectly from mass isotopomer data with the use of a mathematical model of the m...

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Bibliographic Details
Main Authors: Cedersund, G. (Author), Grankvist, N. (Author), Mohit, J. (Author), Nilsson, R. (Author), Sundqvist, N. (Author), Watrous, J. (Author)
Format: Article
Language:English
Published: Public Library of Science 2022
Online Access:View Fulltext in Publisher