Menin Enhances Androgen Receptor-Independent Proliferation and Migration of Prostate Cancer Cells

Menin Enhances Androgen Receptor-Independent Proliferation and Migration of Prostate Cancer Cells

The androgen receptor (AR) is an important therapeutic target for treating prostate cancer (PCa). Moreover, there is an increasing need for understanding the AR-independent progression of tumor cells such as neuroendocrine prostate cancer (NEPC). Menin, which is encoded by multiple endocrine neoplas...

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Bibliographic Details
Main Authors: Cho, E.-J (Author), Choi, J. (Author), Jeong, K. (Author), Kim, E. (Author), Kim, H.S (Author), Kim, J.-H (Author), Kim, T. (Author), Park, J.H (Author), Yoon, K. (Author), Youn, H.-D (Author)
Format: Article
Language:English
Published: Korean Society for Molecular and Cellular Biology 2022
Subjects:
androgen receptor
Cell Line, Tumor
cell proliferation
Cell Proliferation
genetics
human
Humans
male
Male
menin
menin inhibitor
metabolism
metastasis
prostate cancer
prostate tumor
Prostatic Neoplasms
Receptors, Androgen
signal transduction
Signal Transduction
transcription factor
Transcription Factors
tumor cell line
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