Correlation between low expression of protein disulfide isomerase A3 and lymph node metastasis in papillary thyroid carcinoma and poor prognosis: a clinicopathological study of 1,139 cases with long-term follow-up

Correlation between low expression of protein disulfide isomerase A3 and lymph node metastasis in papillary thyroid carcinoma and poor prognosis: a clinicopathological study of 1,139 cases with long-term follow-up

The incidence of papillary thyroid carcinoma (PTC) is increasing worldwide. The biomarkers to identify aggressive types of PTC are limited, illustrating the need to establish reliable novel biomarkers. Protein disulfide isomerase A3 (PDIA3) is a chaperone protein that modulates the folding of newly...

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Bibliographic Details
Main Authors: Chiba, T. (Author), Ebina, A. (Author), Jikuzono, T. (Author), Kure, S. (Author), Mitani, H. (Author), Motoda, N. (Author), Ohashi, R. (Author), Sugitani, I. (Author), Takeuchi, K. (Author), Toda, K. (Author)
Format: Article
Language:English
Published: Japan Endocrine Society 2022
Subjects:
Biomarkers, Tumor
Carcinoma, Papillary
female
Female
follow up
Follow-Up Studies
human
Humans
Immunohistochemistry
lymph node
lymph node metastasis
Lymph node metastasis (LNM)
Lymph Nodes
Lymphatic Metastasis
metabolism
papillary carcinoma
Papillary thyroid carcinoma (PTC)
pathology
prognosis
Prognosis
protein disulfide isomerase
Protein disulfide isomerase A3 (PDIA3)
Protein Disulfide-Isomerases
Retrospective Studies
retrospective study
Thyroid Cancer, Papillary
Thyroid Neoplasms
thyroid tumor
tumor marker
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