The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population

The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population

BACKGROUND: Accumulated studies have pointed out the striking association between variants in or near APOC3, GCKR, PNPLA3, and nonalcoholic fatty liver disease (NAFLD) at various ages from multiple ethnic groups. This association remained unclear in the Chinese Han elderly population, and whether th...

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Bibliographic Details
Main Authors: Bi, Y. (Author), Gu, Z. (Author), He, G. (Author), Liu, B.-C (Author), Niu, W. (Author), Ren, D. (Author), Yuan, F. (Author), Yuan, R. (Author), Zhang, L. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
aged
Aged
case control study
Case-Control Studies
China
GCKR
genetic association
genetic predisposition
Genetic Predisposition to Disease
genetics
genotype
Genotype
human
Humans
Lipase
mediation analysis
membrane protein
Membrane Proteins
NAFLD
nonalcoholic fatty liver
Non-alcoholic Fatty Liver Disease
Polymorphism, Single Nucleotide
single nucleotide polymorphism
triacylglycerol
triacylglycerol lipase
triglyceride
Triglycerides
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