Blood Eosinophils in Chinese COPD Participants and Response to Treatment with Combination Low-Dose Theophylline and Prednisone: A Post-Hoc Analysis of the TASCS Trial

Blood Eosinophils in Chinese COPD Participants and Response to Treatment with Combination Low-Dose Theophylline and Prednisone: A Post-Hoc Analysis of the TASCS Trial

Background and Objectives: The burden of chronic obstructive pulmonary disease (COPD) disproportionately affects patients in low to middle-income countries. Although the Theophylline and Steroids in COPD Study (TASCS) showed no clinical benefit from administering low-dose theophylline and prednisone...

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Bibliographic Details
Main Authors: Barnes, P.J (Author), Berend, N. (Author), Bradbury, T. (Author), Celli, B. (Author), Di Tanna, G.L (Author), Jenkins, C.R (Author), Martin, A. (Author), On behalf of the TASCS Investigators (Author), Scaria, A. (Author), Wen, F.-Q (Author), Zheng, J.-P (Author), Zhong, N.-S (Author)
Format: Article
Language:English
Published: Dove Medical Press Ltd 2022
Subjects:
adult
aged
Aged
Article
bronchodilating agent
Bronchodilator Agents
China
Chinese
chronic obstructive lung disease
Clinical trial
combination drug therapy
controlled study
COPD
COPD assessment test
coughing
disease exacerbation
double blind procedure
Double-Blind Method
drug response
dyspnea
eosinophil
Eosinophil
eosinophil count
eosinophilia
Eosinophils
female
fever
forced expiratory volume
Forced Expiratory Volume
human
human cell
Humans
incidence
leukocyte count
low drug dose
major clinical study
male
Male
middle aged
Middle Aged
multicenter study (topic)
nose obstruction
patient compliance
placebo
post hoc analysis
prednisone
Prednisone
Pulmonary Disease, Chronic Obstructive
randomized controlled trial (topic)
sore throat
spirometry
sputum volume
St. George Respiratory Questionnaire
theophylline
Theophylline
very elderly
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