A Cycle of Inflammatory Adipocyte Death and Regeneration in Murine Adipose Tissue

A Cycle of Inflammatory Adipocyte Death and Regeneration in Murine Adipose Tissue

Adipose tissue (AT) expands by a combination of two fundamental cellular mechanisms: hypertrophic growth of existing adipocytes or through generation of new adipocytes, also known as hyperplastic growth. Multiple lines of evidence suggest a limited capacity for hyperplastic growth of AT in adulthood...

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Bibliographic Details
Main Authors: Guillermier, C. (Author), Kim, S. (Author), Kumar, G.V.N (Author), Monji, A. (Author), Olenchock, B. (Author), Steinhauser, M.L (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
3T3-L1 cell line
3T3-L1 Cells
adipocyte
Adipocytes
adipogenesis
Adipogenesis
animal
Animals
C57BL mouse
Caspase 1
cell death
Cell Death
Diet, High-Fat
genetics
hypertrophy
Hypertrophy
inflammasome
Inflammasomes
inflammation
Inflammation
interleukin 1beta converting enzyme
intra-abdominal fat
Intra-Abdominal Fat
knockout mouse
lipid diet
Mice
Mice, Inbred C57BL
Mice, Knockout
mouse
obesity
Obesity
pathophysiology
physiology
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