Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial

Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial

OBJECTIVE: We tested whether the concurrence of food intake and elevated concentrations of endogenous melatonin, as occurs with late eating, results in impaired glucose control, in particular in carriers of the type 2 diabetes-associated G allele in the melatonin receptor-1B gene (MTNR1B). RESEARCH...

Full description

Bibliographic Details
Main Authors: Baraza, J.C (Author), Dashti, H.S (Author), Florez, J.C (Author), Garaulet, M. (Author), Hernández-Martínez, A.M (Author), Lopez-Minguez, J. (Author), Pérez-Ayala, M. (Author), Saxena, R. (Author), Scheer, F.A.J.L (Author), Vetter, C. (Author), Wang, W. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Blood Glucose
controlled study
crossover procedure
Cross-Over Studies
Diabetes Mellitus, Type 2
genetics
glucose
Glucose
glucose blood level
human
Humans
insulin
Insulin
insulin release
Insulin Secretion
meal
Meals
melatonin 2 receptor
metabolism
MTNR1B protein, human
non insulin dependent diabetes mellitus
physiology
randomized controlled trial
Receptor, Melatonin, MT2
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items