The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities

The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities

Influenza is one of the most relevant respiratory viruses to human health causing annual epidemics, and recurrent pandemics. Influenza disease is principally associated with inappropriate activation of the immune response. Chemokine receptor 5 (CCR5) and its cognate chemokines CCL3, CCL4 and CCL5 ar...

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Bibliographic Details
Main Authors: Ferrero, M.R (Author), Garcia, C.C (Author), Tavares, L.P (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
animal
Animals
biological marker
Biomarkers
CCL3
CCL5
CCR5delta32
CD4+ T lymphocyte
CD8+ T lymphocyte
chemokine receptor 5
chemokine receptor CCR5
disease predisposition
Disease Susceptibility
genetics
host pathogen interaction
Host-Pathogen Interactions
human
Humans
immune response
immunology
influenza
Influenza A virus
Influenza, Human
innate immunity
interleukin 10
interleukin 8
lung alveolus epithelium cell
lung alveolus macrophage
macrophage
macrophage inflammatory protein 1alpha
macrophage inflammatory protein 1beta
memory
metabolism
mutation
Mutation
neutrophil
phenotype
Phenotype
RANTES
Receptors, CCR5
Review
severity of illness index
Severity of Illness Index
tumor immunity
virology
virus load
virus replication
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