The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

Background: The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has only been assessed in small studies. In a pharmacogenetic genome wide association study (GWAS) analysis within the Genomic Investigation of Statin Therapy (GIST) consortium, we investigated...

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Main Authors: Arsenault, B. (Author), Caulfield, M.J (Author), Chasman, D.I (Author), Cupples, A.L (Author), Hitman, G.A (Author), Jukema, W.J (Author), Krauss, R.M (Author), Li, X. (Author), Munroe, P.B (Author), Noordam, R. (Author), on behalf of the GIST consortium and the CHARGE pharmacogenetics working group (Author), Postmus, I. (Author), Psaty, B.M (Author), Rotter, J.I (Author), Smit, R.A.J (Author), Theusch, E. (Author), Trompet, S. (Author), Warren, H.R (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
cardiovascular disease
GWAS
myocardial infarction
pharmacogenetics
statins
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